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Pro9-Substance P

NK-1 Agonist

[Pro9]-Substance P is a highly selective and reversible agonist of the NK-1 tachykinin receptors, demonstrating an EC50 of 0.93 nM. This compound plays a significant role in modulating neurokinin signaling pathways and is instrumental in research focused on pain management, neuroinflammation, and various neurological disorders. Its precise activity profile makes it an invaluable tool for studying the therapeutic potential of NK-1 receptor modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	104486-69-3
Applications	NK-1 Agonist
Formula	C₆₆H₁₀₂N₁₈O₁₃S
Molecular Weight	1387.69
SMILES	C([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC(=O)[C@H]4N(C([C@H](CCCNC(=N)N)N)=O)CCC4)CCCCN)=O)CCC3)CCC(N)=O)=O)CCC(N)=O)=O)=O)(=O)N5[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)CCC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.