Probucol dithiobisphenol (DTBP) is a potent inducer of heme oxygenase 1 (HO-1) with notable antioxidant properties. It effectively inhibits atherosclerotic lesions in the aorta of Apoe−/− mice and promotes re-endothelialization, thereby reducing restenosis in rabbit arterial injury models. This compound is orally active, making it a valuable reagent for investigating vascular health and potential therapeutic applications in cardiovascular diseases.
Probucol dithiobisphenol (DTBP) is a potent inducer of heme oxygenase 1 (HO-1) with notable antioxidant properties. It effectively inhibits atherosclerotic lesions in the aorta of Apoe−/− mice and promotes re-endothelialization, thereby reducing restenosis in rabbit arterial injury models. This compound is orally active, making it a valuable reagent for investigating vascular health and potential therapeutic applications in cardiovascular diseases.
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