Fig. 1 · Structure
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Propargyl-PEG1-Boc
PROTAC Linkers
Propargyl-PEG1-Boc is a versatile PROTAC linker featuring an alkyne functionality that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This reagent is designed for use in click chemistry, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It is particularly valuable for bioconjugation applications and the development of targeted protein degradation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 488150-84-1 |
| Applications | PROTAC Linkers |
| Formula | C10H16O3 |
| Molecular Weight | 184.23 |
| SMILES | O=C(OC(C)(C)C)CCOCC#C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.