Propargyl-PEG4-amine

Catalog No.: A81570
PROTAC Linker
Propargyl-PEG4-amine is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. Featuring an alkyne group, it serves as a click chemistry reagent that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the formation of stable conjugates with azide-containing molecules. This compound is essential for advancing research in drug development and targeted therapeutic strategies.
Grouped product items
Size Price Stock Qty
250mg
$20.00
In stock
1g
$50.00
In stock
5g
$225.00
In stock
10g
$400.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPropargyl-PEG4-amine is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. Featuring an alkyne group, it serves as a click chemistry reagent that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the formation of stable conjugates with azide-containing molecules. This compound is essential for advancing research in drug development and targeted therapeutic strategies.
Product Information
Catalog NumA81570
FormulaC11H21NO4
Molecular Weight231.29
CAS Number1013921-36-2
SMILESNCCOCCOCCOCCOCC#C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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