Fig. 1 · Structure
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Propargyl-PEG4-amine
PROTAC Linker
Propargyl-PEG4-amine is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. Featuring an alkyne group, it serves as a click chemistry reagent that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the formation of stable conjugates with azide-containing molecules. This compound is essential for advancing research in drug development and targeted therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1013921-36-2 |
| Applications | PROTAC Linker |
| Formula | C11H21NO4 |
| Molecular Weight | 231.29 |
| SMILES | NCCOCCOCCOCCOCC#C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.