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Propargyl-PEG4-CH2-methyl ester

PROTAC Linker

Propargyl-PEG4-CH2-methyl ester functions as a PEG-based linker for the synthesis of PROTACs (proteolysis-targeting chimeras). Its alkyne group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the assembly of complex molecular architectures. This compound is essential for researchers aiming to develop targeted protein degradation technologies in drug discovery and chemical biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1872433-63-0
Applications	PROTAC Linker
Formula	C₁₄H₂₄O₆
Molecular Weight	288.34
SMILES	C#CCOCCOCCOCCOCCCC(OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.