Propargyl-PEG4-CH2CO2-NHS is an ADC linker that features a propargyl group and an N-hydroxysuccinimidyl (NHS) moiety. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling selective coupling with amine-containing biomolecules. As a click chemistry reagent, it contains an alkyne functional group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing partners. This versatile tool is essential for enhancing the potency and specificity of targeted therapeutics in bioconjugation applications.
Propargyl-PEG4-CH2CO2-NHS is an ADC linker that features a propargyl group and an N-hydroxysuccinimidyl (NHS) moiety. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling selective coupling with amine-containing biomolecules. As a click chemistry reagent, it contains an alkyne functional group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing partners. This versatile tool is essential for enhancing the potency and specificity of targeted therapeutics in bioconjugation applications.
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