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Propargyl-PEG4-S-PEG4-propargyl

PROTAC Linker

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker designed for the synthesis of PROTAC molecules. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing compounds. Its unique structure and functional properties make it suitable for developing targeted protein degradation strategies in chemical biology research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2055041-17-1
Applications	PROTAC Linker
Formula	C₂₂H₃₈O₈S
Molecular Weight	462.60
SMILES	C#CCOCCOCCOCCOCCSCCOCCOCCOCCOCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.