Fig. 1 · Structure

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Propargyl-PEG6-Br

PROTAC Linker

Propargyl-PEG6-Br is a PEG-based linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an alkyne moiety, this compound facilitates efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-bearing molecules. It plays a crucial role in developing innovative therapeutics by enabling targeted protein degradation, making it a valuable tool for researchers in drug discovery and metabolic studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1973383-30-0
Applications PROTAC Linker
Formula C15H27BrO6
Molecular Weight 383.28
SMILES
C#CCOCCOCCOCCOCCOCCOCCBr

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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