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Propargyl-PEG7-methane

PROTAC Linkers

Propargyl-PEG7-methane is a PEG-based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Propargyl-PEG7-methane facilitates the construction of bifunctional molecules, allowing for targeted protein degradation applications in chemical biology research. Its unique structure and reactivity make it a valuable tool for developing innovative therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2730134-74-2
Applications	PROTAC Linkers
Formula	C₁₈H₃₄O₈
Molecular Weight	378.46
SMILES	COCCOCCOCCOCCOCCOCCOCCOCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.