Fig. 1 · Structure

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Propargyl-PEG9-acid

PROTAC Linker

Propargyl-PEG9-acid is a PEG-based linker specifically designed for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound features an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing biomolecules. Its structural properties enhance biocompatibility and solubility, making it a valuable tool in the development of targeted protein degradation applications in chemical biology and drug discovery.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1613752-50-3
Applications PROTAC Linker
Formula C22H40O11
Molecular Weight 480.55
SMILES
C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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