Propoxur-d7 is the deuterium-labeled analog of Propoxur, a reversible and competitive inhibitor of acetylcholinesterase (AChE). This compound exhibits significant neurotoxic effects by inhibiting AChE activity, leading to increased levels of acetylcholine and subsequent neurological dysfunction. Propoxur-d7 also enhances tumor cell migration and invasion through the promotion of matrix metalloproteinase-2 (MMP-2) expression, driven by reactive oxygen species (ROS) generation and activation of the ERK/Nrf2 signaling pathway. Additionally, Propoxur serves as a carbamate insecticide effective against a variety of pests in turf, forestry, and household settings.
Propoxur-d7 is the deuterium-labeled analog of Propoxur, a reversible and competitive inhibitor of acetylcholinesterase (AChE). This compound exhibits significant neurotoxic effects by inhibiting AChE activity, leading to increased levels of acetylcholine and subsequent neurological dysfunction. Propoxur-d7 also enhances tumor cell migration and invasion through the promotion of matrix metalloproteinase-2 (MMP-2) expression, driven by reactive oxygen species (ROS) generation and activation of the ERK/Nrf2 signaling pathway. Additionally, Propoxur serves as a carbamate insecticide effective against a variety of pests in turf, forestry, and household settings.
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