Propranolol-d7 hydrochloride is a deuterium-labeled β-adrenergic receptor antagonist, exhibiting high affinity for both β1 and β2 adrenergic receptors with Ki values of 1.8 nM and 0.8 nM, respectively. It effectively inhibits [3H]-DHA binding in rat brain membrane preparations, with an IC50 of 12 nM. This compound is widely utilized in research focused on cardiovascular conditions such as hypertension, myocardial infarction, cardiac arrhythmias, and angina pectoris, as well as in studies on pheochromocytoma and hypertrophic cardiomyopathy.
Propranolol-d7 hydrochloride is a deuterium-labeled β-adrenergic receptor antagonist, exhibiting high affinity for both β1 and β2 adrenergic receptors with Ki values of 1.8 nM and 0.8 nM, respectively. It effectively inhibits [3H]-DHA binding in rat brain membrane preparations, with an IC50 of 12 nM. This compound is widely utilized in research focused on cardiovascular conditions such as hypertension, myocardial infarction, cardiac arrhythmias, and angina pectoris, as well as in studies on pheochromocytoma and hypertrophic cardiomyopathy.
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