Propranolol-d7 is a stable isotope-labeled form of Propranolol, a nonselective β-adrenergic receptor (βAR) antagonist. It exhibits high affinity for β1AR and β2AR, with inhibition constants (Ki) of 1.8 nM and 0.8 nM, respectively. Propranolol's capability to inhibit [3H]-DHA binding to rat brain membranes, with an IC50 of 12 nM, makes it a valuable tool for researching conditions such as hypertension, myocardial infarction, cardiac arrhythmias, and other cardiovascular disorders.
Propranolol-d7 is a stable isotope-labeled form of Propranolol, a nonselective β-adrenergic receptor (βAR) antagonist. It exhibits high affinity for β1AR and β2AR, with inhibition constants (Ki) of 1.8 nM and 0.8 nM, respectively. Propranolol's capability to inhibit [3H]-DHA binding to rat brain membranes, with an IC50 of 12 nM, makes it a valuable tool for researching conditions such as hypertension, myocardial infarction, cardiac arrhythmias, and other cardiovascular disorders.
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