Prostaglandin A2

Catalog No.: A30519
Apoptosis Inducer
Prostaglandin A2 (PGA2) is a cyclopentenone prostaglandin that functions as an apoptosis inducer by activating caspase pathways and modulating the p53 signaling pathway. It also activates ERK2 and JNK1/SAPK pathways, contributing to its role in cell death and differentiation. Prostaglandin A2 exhibits antiviral properties against HSV-1 and demonstrates anti-tumor effects, making it relevant in research applications related to colorectal cancer, breast carcinoma, and herpetic keratitis.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProstaglandin A2 (PGA2) is a cyclopentenone prostaglandin that functions as an apoptosis inducer by activating caspase pathways and modulating the p53 signaling pathway. It also activates ERK2 and JNK1/SAPK pathways, contributing to its role in cell death and differentiation. Prostaglandin A2 exhibits antiviral properties against HSV-1 and demonstrates anti-tumor effects, making it relevant in research applications related to colorectal cancer, breast carcinoma, and herpetic keratitis.
Product Information
Catalog NumA30519
FormulaC20H30O4
Molecular Weight334.45
CAS Number13345-50-1
SMILESCCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C=C1)=O)C/C=C\CCCC(O)=O
SynonymsPGA2; Medullin
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