Fig. 1 · Structure
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Prostaglandin D2 methyl ester
Prostaglandin D2 Prodrug
Prostaglandin D2 methyl ester is a prodrug of Prostaglandin D2, primarily targeting the PGD2 receptors. It exhibits binding affinities (Ki values) of 160 nM for murine CRTH2, 175 nM for murine DP, 460 nM for human CRTH2, and 270 nM for human DP. This compound is useful in research applications investigating inflammatory responses, allergic reactions, and sleep regulation, highlighting its importance in pharmacological studies related to prostaglandin signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 49852-81-5 |
| Applications | Prostaglandin D2 Prodrug |
| Formula | C21H34O5 |
| Molecular Weight | 366.49 |
| SMILES | CCCCC[C@H](O)/C=C/[C@@H]1[C@H]([C@H](CC1=O)O)C/C=C\CCCC(OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.