Prostaglandin E2 serinol amide

Catalog No.: A63266
Endogenous Hormone
Prostaglandin E2 serinol amide is a non-hydrolyzable analogue of the endogenous hormone Prostaglandin E2, targeting the inhibition of the hydrolysis of [3H]2-oleoylglycerol. This compound does not convert to PGE2 and, therefore, lacks the capacity to inhibit leukotriene B4 biosynthesis, superoxide production, cellular migration, and the release of antimicrobial peptides. It serves as a useful tool for investigating the roles of prostaglandins in various biological processes.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProstaglandin E2 serinol amide is a non-hydrolyzable analogue of the endogenous hormone Prostaglandin E2, targeting the inhibition of the hydrolysis of [3H]2-oleoylglycerol. This compound does not convert to PGE2 and, therefore, lacks the capacity to inhibit leukotriene B4 biosynthesis, superoxide production, cellular migration, and the release of antimicrobial peptides. It serves as a useful tool for investigating the roles of prostaglandins in various biological processes.
Product Information
Catalog NumA63266
FormulaC23H39NO6
Molecular Weight425.56
CAS Number951209-67-9
SMILESOCC(CO)NC(CCC/C=C\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@@H](O)CCCCC)=O
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