PROTAC SMARCA2/4-degrader-15 is a potent PROTAC degrader targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It demonstrates efficient degradation of SMARCA2 in A549 cells and SMARCA4 in MV411 cells, with DC50 values below 100 nM. This compound is valuable for researchers investigating the role of these proteins in epigenetic regulation and cancer biology.
PROTAC SMARCA2/4-degrader-15 is a potent PROTAC degrader targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It demonstrates efficient degradation of SMARCA2 in A549 cells and SMARCA4 in MV411 cells, with DC50 values below 100 nM. This compound is valuable for researchers investigating the role of these proteins in epigenetic regulation and cancer biology.
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