Fig. 1 · Structure
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PROTAC TG2 degrader-2
TG2 Degrader
PROTAC TG2 Degrader-2 is a selective degrader that targets Transglutaminase 2 (TG2). This compound effectively inhibits cell migration and reduces TG2 levels in ovarian cancer cells, making it a valuable tool for research into ovarian cancer biology. Its ability to modulate TG2 offers insights into potential therapeutic strategies against this malignancy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 3033465-51-6 |
| Applications | TG2 Degrader |
| Formula | C47H57N9O6S |
| Molecular Weight | 876.08 |
| SMILES | O=C(CCOCCN(C1=CC(C)=NC(NC2=CC=C(NC(CC3=CC=CC=C3)=O)C=C2)=N1)C)N[C@@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)C[C@@H](O)C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.