Fig. 1 · Structure

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PROTAC TG2 Degrader-3

TG2 Degrader

PROTAC TG2 Degrader-3 functions as a targeted protein degrader specifically for transglutaminase 2 (TG2). This compound effectively inhibits the adhesion and migration of ovarian cancer cells, making it a valuable tool for research focused on ovarian cancer biology and therapeutics. By facilitating the degradation of TG2, it provides insights into the modulation of cancer cell behavior and the potential development of novel treatments.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3054388-18-7
Applications TG2 Degrader
Formula C51H62FN9O7S2
Molecular Weight 996.22
SMILES
CN(CCOCCOCCSC(C)(C)[C@@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)NC(C4(F)CC4)=O)C5=NC(NC6=CC=C(NC(CC7=CC=CC=C7)=O)C=C6)=NC(C)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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