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Protoneodioscin

Catalog No.: B19118
Anticancer Agent
Protoneodioscin is a furostanol saponin derived from the rhizomes of Dioscorea collettii var. hypoglauca, acting primarily as an anticancer agent. This compound demonstrates selective cytotoxicity towards multiple cancer cell lines, particularly leukemia, while displaying no efficacy against colon and renal cancer. Protoneodioscin is a valuable reagent for research focused on leukemia and other related malignancies.
Protoneodioscin 60478-69-5 Anticancer Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProtoneodioscin is a furostanol saponin derived from the rhizomes of Dioscorea collettii var. hypoglauca, acting primarily as an anticancer agent. This compound demonstrates selective cytotoxicity towards multiple cancer cell lines, particularly leukemia, while displaying no efficacy against colon and renal cancer. Protoneodioscin is a valuable reagent for research focused on leukemia and other related malignancies.
Product Information
Catalog NumB19118
FormulaC51H84O22
Molecular Weight1049.20
CAS Number60478-69-5
SMILESC[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H]([C@](O)(O3)CC[C@H](C)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)([H])[C@@]5([H])[C@]([C@@]6(C(C[C@H](CC6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)=CC5)C)([H])CC1
SynonymsNSC-698789
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