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Protriptyline-d3

Stable Isotope

Protriptyline-d3 is a deuterated analog of the tricyclic antidepressant Protriptyline, serving as a stable isotope for research applications. It exerts potent inhibition of acetylcholinesterase (AChE) with an IC50 value of 0.06 mM and effectively inhibits amyloid beta (Aβ) self-assembly. This compound is valuable for studying the mechanisms underlying depression and Alzheimer's disease.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	136765-50-9
Applications	Stable Isotope
Formula	C₁₉H₁₈D₃N
Molecular Weight	266.40
SMILES	[2H]C([2H])([2H])NCCCC1C2=C(C=CC=C2)C=CC3=C1C=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.