Prucalopride hydrochloride is a selective and specific agonist for the 5-HT4 receptor, with high affinity identified by pKis of 8.6 and 8.1 for the human 5-HT4a and 4b subtypes, respectively. This compound enhances intestinal motility by facilitating the regeneration of the intestinal nervous system, as demonstrated in rodent models. Additionally, Prucalopride hydrochloride exhibits anticancer properties through the inhibition of the PI3K/AKT/mTOR signaling pathway. Its applications are relevant in research focused on chronic constipation, pseudo-intestinal obstruction, and cancer.
Prucalopride hydrochloride is a selective and specific agonist for the 5-HT4 receptor, with high affinity identified by pKis of 8.6 and 8.1 for the human 5-HT4a and 4b subtypes, respectively. This compound enhances intestinal motility by facilitating the regeneration of the intestinal nervous system, as demonstrated in rodent models. Additionally, Prucalopride hydrochloride exhibits anticancer properties through the inhibition of the PI3K/AKT/mTOR signaling pathway. Its applications are relevant in research focused on chronic constipation, pseudo-intestinal obstruction, and cancer.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
