Pruvanserin hydrochloride

Catalog No.: A29885
5-HT2A Receptor Antagonist
Pruvanserin hydrochloride is a selective antagonist of the serotonin 5-HT2A receptor, exhibiting IC50 values of 0.35 nM and 1 nM for human and rat receptors, respectively. This compound is primarily utilized in scientific research focused on schizophrenia, aiding in the exploration of therapeutic strategies targeting serotonergic pathways. Its high selectivity and potency make it a valuable tool in the study of neuropsychiatric disorders associated with serotonin dysregulation.
Grouped product items
Size Price Stock Qty
1mg
$180.00
In stock
5mg
$470.00
In stock
10mg
$690.00
In stock
25mg
$1,560.00
In stock
50mg
$2,780.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPruvanserin hydrochloride is a selective antagonist of the serotonin 5-HT2A receptor, exhibiting IC50 values of 0.35 nM and 1 nM for human and rat receptors, respectively. This compound is primarily utilized in scientific research focused on schizophrenia, aiding in the exploration of therapeutic strategies targeting serotonergic pathways. Its high selectivity and potency make it a valuable tool in the study of neuropsychiatric disorders associated with serotonin dysregulation.
Product Information
Catalog NumA29885
FormulaC22H22ClFN4O
Molecular Weight412.89
CAS Number443144-27-2
SMILESN#CC1=CNC2=C1C=CC=C2C(N3CCN(CC3)CCC4=CC=C(C=C4)F)=O.Cl
SynonymsEMD 281014; LY 2422347 hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2