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Pruvanserin

Catalog No.: A45874
5-HT2A receptor Antagonist
Pruvanserin is a selective antagonist of the 5-HT2A receptor, demonstrating significant potential in modulating serotonergic pathways. This compound has been shown to alleviate tactile allodynia in diabetic rat models, indicating its usefulness in pain research. Additionally, Pruvanserin is being explored for its applications in studying insomnia and related sleep disorders.
Pruvanserin 443144-26-1 5-HT2A receptor Antagonist
Grouped product items
Size Price Stock Qty
5mg
$115.00
In stock
10mg
$190.00
In stock
25mg
$395.00
In stock
50mg
$615.00
In stock
100mg
$920.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPruvanserin is a selective antagonist of the 5-HT2A receptor, demonstrating significant potential in modulating serotonergic pathways. This compound has been shown to alleviate tactile allodynia in diabetic rat models, indicating its usefulness in pain research. Additionally, Pruvanserin is being explored for its applications in studying insomnia and related sleep disorders.
Product Information
Catalog NumA45874
FormulaC22H21FN4O
Molecular Weight376.43
CAS Number443144-26-1
SMILESN#CC1=CNC2=C1C=CC=C2C(N3CCN(CC3)CCC4=CC=C(C=C4)F)=O
SynonymsEMD 281014 free base; LY 2422347
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > 5-HT Receptors