Fig. 1 · Structure
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Pruvanserin
5-HT2A receptor Antagonist
Pruvanserin is a selective antagonist of the 5-HT2A receptor, demonstrating significant potential in modulating serotonergic pathways. This compound has been shown to alleviate tactile allodynia in diabetic rat models, indicating its usefulness in pain research. Additionally, Pruvanserin is being explored for its applications in studying insomnia and related sleep disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 443144-26-1 |
| Applications | 5-HT2A receptor Antagonist |
| Formula | C22H21FN4O |
| Molecular Weight | 376.43 |
| Synonyms | EMD 281014 free base; LY 2422347 |
| SMILES | N#CC1=CNC2=C1C=CC=C2C(N3CCN(CC3)CCC4=CC=C(C=C4)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.