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PS1097

Antiviral Agent

PS1097 is a broad-spectrum antiviral agent that targets the BVDV RNA-dependent RNA polymerase (RdRp), exhibiting an IC50 of 0.64 μM. This compound selectively reduces RTN3 protein levels and partially decreases RTN3 mRNA without affecting other endoplasmic reticulum-resident proteins. PS1097 demonstrates significant antiviral activity against Zika virus and other viruses that utilize the endoplasmic reticulum for replication, including Bovine Viral Diarrhea Virus (BVDV). It is suitable for research into various viral infections, such as COVID-19, chikungunya, and West Nile viruses.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1822320-58-0
Applications	Antiviral Agent
Formula	C₁₅H₈ClN₃OS
Molecular Weight	313.76
SMILES	O=C1NC2=C(N=C1C3=CC=CS3)C(Cl)=C4N=CC=CC4=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.