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Catalog No.: A12260

Ecto-5'-Nucleotidase (CD73) inhibitor


PSB-12379 Chemical Structure

CAS NO. 1802226-78-3

PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).

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Biological Activity

PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.4 mL 97.02 mL 194.04 mL
0.5 mM 3.88 mL 19.4 mL 38.81 mL
1 mM 1.94 mL 9.7 mL 19.4 mL
5 mM 0.39 mL 1.94 mL 3.88 mL

*The above data is based on the productmolecular weight 515.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12260
Actions Inhibitor
CAS No. 1802226-78-3
Formula C18H23N5O9P2
M. Wt 515.35
Purity >98%
Synonyms PSB12379, PSB 12379
SMILES O[[email protected]@H]([[email protected]]1O)[[email protected]@H](COP(CP(O)(O)=O)(O)=O)O[[email protected]]1N(C=N2)C3=C2C(NCC4=CC=CC=C4)=NC=N3

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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