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Biological Activity
PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.4 mL | 97.02 mL | 194.04 mL |
| 0.5 mM | 3.88 mL | 19.4 mL | 38.81 mL |
| 1 mM | 1.94 mL | 9.7 mL | 19.4 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.88 mL |
*The above data is based on the productmolecular weight 515.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12260 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1802226-78-3 |
| Formula | C18H23N5O9P2 |
| M. Wt | 515.35 |
| Purity | >98% |
| Synonyms | PSB12379, PSB 12379 |
| SMILES | O[[email protected]@H]([[email protected]]1O)[[email protected]@H](COP(CP(O)(O)=O)(O)=O)O[[email protected]]1N(C=N2)C3=C2C(NCC4=CC=CC=C4)=NC=N3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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