Fig. 1 · Structure

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PSEN1-IN-3

Gamma Secretase Complex Modulator

PSEN1-IN-3 is a modulator of the gamma secretase complex, primarily targeting the presenilin-1 component. This compound plays a critical role in the regulation of amyloid precursor protein (APP) processing, thereby influencing amyloid-beta peptide production. PSEN1-IN-3 is utilized in research related to Alzheimer's disease and other neurodegenerative disorders, aiding in the investigation of gamma secretase's role in pathology and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1093975-58-6
Applications Gamma Secretase Complex Modulator
Formula C25H22F4N6O2
Molecular Weight 514.47
SMILES
COC1=CC(C2=CN([C@H]3CCC(C(F)=CC=C4)=C4N(CC(F)(F)F)C3=O)N=N2)=CC=C1N5C=NC(C)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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