Fig. 1 · Structure
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Pseudocoptisine chloride
AChE Inhibitor
Pseudocoptisine chloride is a quaternary alkaloid derived from the benzylisoquinoline structure, isolated from Corydalis tuber. This compound functions as an acetylcholinesterase (AChE) inhibitor, demonstrating an IC50 of 12.8 μM. Pseudocoptisine chloride exhibits notable anti-inflammatory and anti-amnestic properties, making it a valuable reagent for research related to neurodegenerative diseases and cognitive function studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 30044-78-1 |
| Applications | AChE Inhibitor |
| Formula | C19H14ClNO4 |
| Molecular Weight | 355.77 |
| Synonyms | Isocoptisine chloride |
| SMILES | C12=[N+](C=C3C(C=C4C(OCO4)=C3)=C2)CCC5=CC6=C(OCO6)C=C15.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.