PT-88 is a highly selective inhibitor of the mTOR (Mammalian Target of Rapamycin) pathway, demonstrating an IC50 of 1.2 nM. This compound effectively inhibits both mTORC1 and mTORC2 complexes, which play critical roles in regulating cell growth, proliferation, and survival. PT-88 is suitable for investigating the involvement of mTOR in tumorigenesis and development, particularly in breast cancer research.
PT-88 is a highly selective inhibitor of the mTOR (Mammalian Target of Rapamycin) pathway, demonstrating an IC50 of 1.2 nM. This compound effectively inhibits both mTORC1 and mTORC2 complexes, which play critical roles in regulating cell growth, proliferation, and survival. PT-88 is suitable for investigating the involvement of mTOR in tumorigenesis and development, particularly in breast cancer research.
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