Fig. 1 · Structure
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Pt(DACH)(OH)2(ox)
Phorbiplatin Intermediate
Pt(DACH)(OH)2(ox) is a Pt(IV) complex that serves as a key intermediate in the synthesis of phorbiplatin. It reacts with the N-hydroxysuccinimide ester of Pyropheophorbide-a to produce phorbiplatin, a potent antitumor prodrug known for its efficacy against various cancers. This compound is valuable for research in cancer therapeutics and drug development, particularly in the context of platinum-based chemotherapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 111321-67-6 |
| Applications | Phorbiplatin Intermediate |
| Formula | C8H16N2O6Pt |
| Molecular Weight | 431.31 |
| Synonyms | Dihydroxy Oxaliplatin-Pt(IV) |
| SMILES | [OH-][Pt+4]12([NH2][C@@]3([H])[C@](CCCC3)([H])[NH2]1)([O-]C(C([O-]2)=O)=O)[OH-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.