PTC-510 free base

Catalog No.: A73291
Endogenous Metabolite
PTC-510 Free Base is a selective inhibitor of hypoxia-induced VEGF expression in tumor cells. It effectively reduces endogenous VEGF production under hypoxic conditions, demonstrating significant activity in controlling tumor growth while minimizing associated toxicity. This compound offers a novel therapeutic approach to overcome the limitations of existing anti-VEGF therapies, making it a valuable tool for cancer research and therapeutic development.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPTC-510 Free Base is a selective inhibitor of hypoxia-induced VEGF expression in tumor cells. It effectively reduces endogenous VEGF production under hypoxic conditions, demonstrating significant activity in controlling tumor growth while minimizing associated toxicity. This compound offers a novel therapeutic approach to overcome the limitations of existing anti-VEGF therapies, making it a valuable tool for cancer research and therapeutic development.
Product Information
Catalog NumA73291
FormulaC26H26BrN3O2S
Molecular Weight524.47
CAS Number865531-74-4
SMILESO=C(N1C2CCCCC2)C3CC4=C(NC5=C4C=C(C=C5)Br)C(N3C1=S)C6=CC=C(C=C6)OC
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