Fig. 1 · Structure
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PTC-510 free base
Cat. No.
A73291
CAS
865531-74-4
Endogenous Metabolite
PTC-510 Free Base is a selective inhibitor of hypoxia-induced VEGF expression in tumor cells. It effectively reduces endogenous VEGF production under hypoxic conditions, demonstrating significant activity in controlling tumor growth while minimizing associated toxicity. This compound offers a novel therapeutic approach to overcome the limitations of existing anti-VEGF therapies, making it a valuable tool for cancer research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 865531-74-4 |
| Applications | Endogenous Metabolite |
| Formula | C26H26BrN3O2S |
| Molecular Weight | 524.47 |
| SMILES | O=C(N1C2CCCCC2)C3CC4=C(NC5=C4C=C(C=C5)Br)C(N3C1=S)C6=CC=C(C=C6)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.