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pTH-Related Protein (7-34) amide (human, mouse, rat)

Catalog No.: A85479
PTH Antagonist
pTH-Related Protein (7-34) amide (human, mouse, rat) serves as a potent antagonist of parathyroid hormone (PTH). This peptide plays a crucial role in studies examining calcium homeostasis and bone metabolism. It is particularly useful in research focused on bone density regulation, osteoclast activity, and therapeutic strategies for managing metabolic bone diseases.
pTH-Related Protein (7-34) amide (human, mouse, rat) 115695-30-2 PTH Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionpTH-Related Protein (7-34) amide (human, mouse, rat) serves as a potent antagonist of parathyroid hormone (PTH). This peptide plays a crucial role in studies examining calcium homeostasis and bone metabolism. It is particularly useful in research focused on bone density regulation, osteoclast activity, and therapeutic strategies for managing metabolic bone diseases.
Product Information
Catalog NumA85479
FormulaC153H247N49O37
Molecular Weight3364.90
CAS Number115695-30-2
SequenceLeu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2
Sequence shorteningLLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2
SMILES[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@H](C(N)=O)C)=O)[C@@H](C)O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)C)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)=O)CC(C)C)=O)=O)(CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC6=CN=CN6)NC([C@@H](NC([C@H](CC(C)C)N)=O)CC(C)C)=O)=O)CC(O)=O)=O)CCCCN)=O)=O)CCCCN)=O)CO)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O
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Endocrinology-Hormones > Thyroid Hormone Receptor