Fig. 1 · Structure

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PTP Inhibitor IV

PTP Inhibitor

PTP Inhibitor IV is a selective inhibitor of protein tyrosine phosphatases (PTPs), specifically targeting DUSP14 and exhibiting a half-maximal inhibitory concentration (IC50) of 5.21 μM. It effectively inhibits various PTPs including SHP-2, PTP1B, PTP-ε, PTP Meg-2, PTP-σ, PTP-β, and PTP-μ, with IC50 values ranging from 1.8 μM to 20 μM. This reagent is valuable for studies investigating the roles of specific phosphatases in signaling pathways, cellular processes, and disease mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 329317-98-8
Applications PTP Inhibitor
Formula C26H26F6N2O4S2
Molecular Weight 608.62
SMILES
CC(C1=CC=C(C(C)(C2=CC=C(NS(C(F)(F)F)(=O)=O)C=C2)C)C=C1)(C3=CC=C(NS(C(F)(F)F)(=O)=O)C=C3)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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