Fig. 1 · Structure
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PTP1B-IN-13
Phosphatase Inhibitor
PTP1B-IN-13 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), acting on the allosteric site with an IC50 value of 1.59 μM. This compound demonstrates significant inhibitory activity, making it a valuable tool for studying the role of PTP1B in cellular signaling pathways. Research applications include investigations into metabolic disorders, obesity, and insulin resistance, facilitating the exploration of potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 650621-20-8 |
| Applications | Phosphatase Inhibitor |
| Formula | C24H25N3O3S2 |
| Molecular Weight | 467.60 |
| SMILES | O=C(CCC1=CC=CC=C1)NC(NC2=CC=C(S(=O)(NC3=CC=C(C)C(C)=C3)=O)C=C2)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.