Fig. 1 · Structure
Documents & Downloads
PTP1B-IN-14
Phosphatase Inhibitor
PTP1B-IN-14 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), exhibiting an IC50 value of 0.72 μM. This compound targets the allosteric site of PTP1B, providing a unique mechanism to regulate its phosphatase activity. PTP1B-IN-14 is essential for research applications focused on metabolic disorders, obesity, and diabetes, as it plays a crucial role in insulin signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 724451-35-8 |
| Applications | Phosphatase Inhibitor |
| Formula | C27H19N5O3S4 |
| Molecular Weight | 589.73 |
| SMILES | O=C(CSC1=NC2=C(S1)C=C(N3C(C4=C(C3=O)C=CC=C4)=O)C=C2)NC5=NN=C(SCC6=CC(C)=CC=C6)S5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.