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PTP1B-IN-16

PTP1B Inhibitor

PTP1B-IN-16 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), exhibiting a Ki value of 12.6 μM. This benzimidazole derivative is primarily utilized in research focused on type 2 diabetes. By inhibiting PTP1B, this compound may contribute to the modulation of insulin signaling pathways, thereby providing insights into potential therapeutic strategies for metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2848581-86-0
Applications	PTP1B Inhibitor
Formula	C₂₆H₁₈ClN₃O₄S
Molecular Weight	503.96
SMILES	O=C(NC1=CC=C(C=C1)C(O)=O)CSC2=NC3=C(N2)C=C(C(OC4=CC5=CC=CC=C5C=C4)=C3)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.