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PTP1B-IN-20

PTP1B Inhibitor

PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC50 value of 1.05 μM, demonstrating a significant preference over T-cell protein tyrosine phosphatase (TCPTP), which has an IC50 of 78.0 μM. PTP1B plays a crucial role in insulin signaling and glucose homeostasis, making this compound a valuable tool for research in type 2 diabetes and metabolic disorders. Its specificity for PTP1B enables detailed studies on the modulation of this enzyme and its implications in insulin resistance and related diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3001295-81-1
Applications	PTP1B Inhibitor
Formula	C₂₆H₂₈O₁₅
Molecular Weight	580.49
SMILES	OC1=C(C2=C(C(C3=C(C2=O)C=C(C(C)=C3O)O[C@H]4[C@H](O)[C@H]([C@@H]([C@H](O4)CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)O)O)=O)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.