Fig. 1 · Structure
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PTP1B-IN-3 diammonium
PTP1B Inhibitor
PTP1B-IN-3 diammonium is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 120 nM. This compound effectively targets PTP1B and T cell protein tyrosine phosphatase (TCPTP), making it significant for studies in diabetes and cancer research. Its demonstrated antidiabetic and anticancer activities position PTP1B-IN-3 diammonium as a valuable tool for exploring therapeutic strategies in these diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2702673-78-5 |
| Applications | PTP1B Inhibitor |
| Formula | C12H13BrF2N3O3P |
| Molecular Weight | 396.12 |
| SMILES | BrC1=C(C(F)(P(O)(O)=O)F)C=C2C(C=CC(C#N)=C2)=C1.N.N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.