Fig. 1 · Structure
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PTPN2-IN-1
PTPN2 Inhibitor
PTPN2-IN-1 is a potent inhibitor of Protein Tyrosine Phosphatase N2 (PTPN2) with an IC50 of ≤5 μM. This compound has demonstrated efficacy in inhibiting cell growth in B16F10 melanoma cells, making it a valuable tool for research in cancer biology. Its specific target engagement provides insights into the regulatory roles of PTPN2 in cellular signaling pathways and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3033936-66-9 |
| Applications | PTPN2 Inhibitor |
| Formula | C16H16FN3O5S2 |
| Molecular Weight | 413.44 |
| SMILES | O=C(C1=CC2=C(F)C(N3CC(NS3(=O)=O)=O)=C(O)C=C2S1)NCCC4CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.