Fig. 1 · Structure
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Pulixin
Antimalarial agent
Pulixin is an antimalarial agent that disrupts the binding of FREP1 to Plasmodium falciparum-infected cell lysate. It effectively prevents the transmission of the parasite to mosquitoes, exhibiting an EC50 of 11 µM. Additionally, Pulixin demonstrates potent inhibition of the asexual-stage proliferation of P. falciparum, with an EC50 of 47 nM, making it a valuable tool for malaria research and development of potential therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2826264-81-5 |
| Applications | Antimalarial agent |
| Formula | C14H11NO4 |
| Molecular Weight | 257.24 |
| SMILES | O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.