Fig. 1 · Structure
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Pumiloside
AchE Inhibitor
Pumiloside is a natural compound isolated from Nauclea officinalis that functions as an acetylcholinesterase (AChE) inhibitor, demonstrating an IC50 value of 118.36 μM. This compound is of significant interest for research applications related to neurodegenerative disorders, where modulation of cholinergic signaling may be beneficial. Pumiloside's ability to inhibit AChE positions it as a potential candidate for the development of therapeutic agents targeting cognitive decline.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 126722-26-7 |
| Applications | AchE Inhibitor |
| Formula | C26H28N2O9 |
| Molecular Weight | 512.51 |
| SMILES | O=C1N2[C@](C[C@]3([H])C1=CO[C@H]([C@@H]3C=C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)([H])C5=C(C(C6=CC=CC=C6N5)=O)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.