Fig. 1 · Structure

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PXS-5153A

Cat. No. A18757 CAS 2125956-82-1

LOXL2/LOXL3 inhibitor

PXS-5153A is a novel mechanism based, fast-acting, dual LOXL2/LOXL3 inhibitor, which was used to interrogate the role of these enzymes in models of collagen crosslinking and fibrosis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2125956-82-1
Applications LOXL2/LOXL3 inhibitor
Formula C20H25Cl2FN4O2S
Molecular Weight 475.41
Synonyms PXS-5153
SMILES
CC(N1C/C(F)=C/CN)=C(C2=CC=CC(S(N(C)C)(=O)=O)=C2)C3=C1C=CC=N3.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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