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Pyrene-PEG5-propargyl

PROTAC Linker

Pyrene-PEG5-propargyl is a PEG-based PROTAC linker designed for efficient synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to target proteins, enabling ubiquitination and subsequent degradation. Its unique structure enhances solubility and stability, making it suitable for various biological applications in targeted protein degradation research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1817735-33-3
Applications	PROTAC Linker
Formula	C₃₀H₃₃NO₆
Molecular Weight	503.59
SMILES	O=C(C1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1)NCCOCCOCCOCCOCCOCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.