Fig. 1 · Structure
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Pyridaben
METI Acaricide
Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that disrupts mitochondrial function by selectively targeting complex I (NADH dehydrogenase), with an IC50 value of 2.4 nM in assays using rat liver and bovine heart mitochondria. This compound promotes the generation of harmful oxygen and nitrogen radicals, contributing to its acaricidal activity. Pyridaben is also known to significantly inhibit mitochondrial nitric oxide synthase (mtNOS) in rat mitochondria, making it valuable for research on mitochondrial dysfunction and oxidative stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 96489-71-3 |
| Applications | METI Acaricide |
| Formula | C19H25ClN2OS |
| Molecular Weight | 364.93 |
| SMILES | O=C1C(Cl)=C(SCC2=CC=C(C(C)(C)C)C=C2)C=NN1C(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.