Fig. 1 · Structure
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Q134R
NFAT Inhibitor
Q134R is a potent inhibitor of the nuclear factor of activated T cells (NFAT) signaling pathway. This neuroprotective hydroxyquinoline derivative is capable of crossing the blood-brain barrier, making it relevant for studies of central nervous system disorders. Q134R holds promise for research applications in Alzheimer's disease and other aging-related conditions, providing insights into the mechanisms of neuroprotection and cellular signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2022949-46-6 |
| Applications | NFAT Inhibitor |
| Formula | C22H17F3N4O |
| Molecular Weight | 410.39 |
| SMILES | OC1=C(N=CC=C2)C2=CC=C1[C@@H](C3=CC=C(C(F)(F)F)C=C3)NC4=NC=CC(C)=N4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.