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Form	MW
QBS10072S dihydrochloride This page	406.18
QBS10072S	333.25

QBS10072S dihydrochloride

Antitumor Agent

QBS10072S dihydrochloride is a bifunctional chemotherapeutic agent designed to target LAT1, facilitating its capacity to penetrate the blood-brain barrier. It demonstrates significant inhibitory potency against LAT1-mediated substrate uptake (IC50 = 21 μM), while showing much lower activity against LAT2 (IC50 = 1100 μM). This compound enters LAT1-expressing tumor cells through active transport, subsequently inducing DNA interstrand crosslinking that leads to DNA damage and cell death. QBS10072S dihydrochloride is suitable for research focused on glioblastoma and aggressive T-cell lymphoma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	1802735-31-4
Applications	Antitumor Agent
Formula	C₁₅H₂₄Cl₄N₂O₂
Molecular Weight	406.18
SMILES	ClCCN(C1=CC(C[C@H](N)CC(O)=O)=C(C=C1)C)CCCl.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.