Fig. 1 · Structure
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QSY 21 NHS
FRET Dark Quencher
QSY 21 NHS is a dark quencher that serves as an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. Operating within a wavelength range of 540-750 nm, it is primarily utilized in Förster resonance energy transfer (FRET) applications, where it does not exhibit fluorescence under standard conditions. The NHS ester functionality enables labeling of primary amines in proteins, amine-modified oligonucleotides, and various amine-containing molecules. Additionally, QSY 21 NHS can be conjugated with dendritic poly-L-lysine to facilitate intramolecular quenching of Cy5 fluorescence.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 304014-13-9 |
| Applications | FRET Dark Quencher |
| Formula | C45H39ClN4O7S |
| Molecular Weight | 815.33 |
| SMILES | O=C(C1CCN(S(=O)(C2=C(C3=C4C=CC(N5C6=C(CC5)C=CC=C6)=CC4=[O+]C7=C3C=CC(N8C9=C(CC8)C=CC=C9)=C7)C=CC=C2)=O)CC1)ON%10C(CCC%10=O)=O.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.