Fig. 1 · Structure
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Quinacrine
Antimalarial Agent
Quinacrine is an antimalarial agent that targets nucleic acids. It exhibits antitumor properties and selectively inhibits human aldehyde oxidase with an IC50 of 3.3 μM. Additionally, Quinacrine binds to DNA and RNA, acting as a fluorescent stain for fixed cells, with excitation and emission wavelengths of 436 and 525 nm, respectively. Its biological activities make it valuable for research in malaria treatment and cancer studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 83-89-6 |
| Applications | Antimalarial Agent |
| Formula | C23H30ClN3O |
| Molecular Weight | 399.96 |
| Synonyms | Acriquine |
| SMILES | CC(NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.