Fig. 1 · Structure
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(R)-4-Methoxydalbergione
Urease Inhibitor
(R)-4-Methoxydalbergione is a potent urease inhibitor, demonstrating IC50 values of 59.72 μM and 67.33 μM against Bacillus pasteurii urease and Jack bean urease, respectively. This compound also exhibits antiplasmodial activity, making it relevant for malaria research. Isolated from Ranunculus repens, (R)-4-Methoxydalbergione serves as a valuable reagent for studies in enzymatic inhibition and potential therapeutic applications in infectious diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4646-86-0 |
| Applications | Urease Inhibitor |
| Formula | C16H14O3 |
| Molecular Weight | 254.28 |
| SMILES | C=C[C@H](C1=CC=CC=C1)C(C(C=C2OC)=O)=CC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.