Fig. 1 · Structure
Documents & Downloads
(R)-Birabresib
Isomer
(R)-Birabresib is the isomer of Birabresib, serving as a valuable experimental control in biochemical research. It functions as a potent inhibitor of bromodomain proteins BRD2, BRD3, and BRD4, with reported IC50 values ranging from 92 to 112 nM. This compound is primarily utilized in studies focused on epigenetic regulation and the therapeutic potential of bromodomain inhibition in various diseases, including cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1983196-25-3 |
| Applications | Isomer |
| Formula | C25H22ClN5O2S |
| Molecular Weight | 491.99 |
| Synonyms | (R)-OTX-015; (R)-MK-8628 |
| SMILES | ClC1=CC=C(C(C2=C(N3C4=NN=C3C)SC(C)=C2C)=N[C@@H]4CC(NC5=CC=C(O)C=C5)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.